Uses of Modafinil
Modafinil improves cognitive ability and has been suggested for treatment of methamphetamine addicts, who frequently have prefrontal cortical function pronlems. Tests on animals show that modafinil improves spatial task proficiency – thought to be located in the hippocampal part of the brain. BOLD fMRI tests show the people on modafinil have less amygdala reactivity when presented with threats. Modafinil makes your brave? It’s not that simple, but the medication does change the brain in the short run. A recent German review showed that the drug can do only so much in maintaining wakefullness, however. Eventually, people need to sleep.
Unlike amphetamines and Ritalin, Modafinil does not act as a direct or indirect dopamine receptor agonist nor does it bind to possibly relevant receptors including those for norepinephrine, serotonin, gamma-aminobutyric acid (GABA), and dopamine uptake.
French scientists have recently determined that modafinil can help memory and other forms of mental performance in sleep-deprived mice. This meshes with reports of many humans who take modafinil and find the same thing.